The researchers of the Icahn School of Medicine at Mount Sinai, have successfully made a major contribution in the field of HIV cures. Their idea about a vaccine is novel for HIV treatment.
— ViiV Healthcare (@ViiVHC) July 22, 2019
HIV treatment: The vaccine is tested on monkeys
The vaccine for HIV treatment has been officially tested on monkeys. The reports reveal that the attempt is a successful one. The vaccine can protect monkeys from the HIV virus, which is an AIDS-causing virus.
HIV has been a topic of hush-hush among the common folks. But the scientific contributors are constantly looking for cures for this deadly disease.
It is indeed a deadly disease; an HIV positive person experiences a significant decline in his or her immunity. This immunity loss weakens the body and makes them prone to many more diseases.
Research and development
The vaccine researchers shared that their first step was identifying a specific part of the virus. This part of the virus, when binds to the antibodies of the body lead to its own destruction. Our bodies are designed to destroy any foreign entrant. And in this case, it is the virus.
— Juliyan Gunasinghe (@juliyan_g) July 15, 2019
Soon after this pertinent identification, which is known as the V1V2 loop of the gp120 envelope protein; the researchers further started working on the vaccine for HIV treatment that induces antibodies with a similar function. This entire process of identification and vaccine creation is known as “reverse vaccinology.”
In this specific study by the Icahn School of Medicine, the monkeys are inoculated with gp120 DNA along with three new recombinant or cloned proteins. These novel proteins carry the V1V2 region and comprise a number of antiviral functions.
Susan Zolla-Pazner is a Ph.D., Professor of Medicine and Microbiology at the Icahn School of Medicine at Mount Sinai and the lead author of this study. She shared that she along with her team has been working on this project for over a decade and the newly developed vaccine is extremely safe.
Every person who is vaccinated will be a hundred percent infection-free. A vigilant reduction of HIV infection has been done for the making of these antibodies.
Two recent studies shed light on the loss of T cell immune function during #HIV infection and open the door to metabolic treatment options that could ultimately cure HIV.https://t.co/QcvJRnorUF#hivcure pic.twitter.com/ACcFjwBgTJ
— defeatHIV (@defeatHIV) July 15, 2019
There are no official announcements about the trial of the new vaccine for HIV treatment on humans. However, the lead author has shared that the vaccine may work on humans as well. This achievement will thereby lead to the immunology of the human body from a fatal virus like HIV.
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